Rheumatoide Arthritis: IL-6-Serumspiegel sagt Therapieansprechen voraus
نویسندگان
چکیده
Interleukin-6 (IL-6) spielt eine wichtige Rolle bei der Pathogenese rheumatoiden Arthritis (RA). Mittlerweile sind gegen den IL-6-Signalweg gerichtete monoklonale Antikörper (z. B. Sarilumab) zur Therapie RA zugelassen. Lässt sich anhand des initialen IL-6-Serumspiegels das Therapieansprechen voraussagen? Dieser Frage ging ein Team internationaler Wissenschaftler mithilfe einer post hoc-Analyse von Daten zweier Phase III-Studien nach.
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ژورنال
عنوان ژورنال: Aktuelle Rheumatologie
سال: 2021
ISSN: ['1438-9940', '0341-051X']
DOI: https://doi.org/10.1055/a-1295-6188